Please use this identifier to cite or link to this item:https://hdl.handle.net/20.500.12259/60087
Type of publication: Konferencijų tezės nerecenzuojamuose leidiniuose / Conference theses in non-peer-reviewed publications (T2)
Field of Science: Biologija / Biology (N010)
Author(s): Radzijevskaja, Jana;Paulauskas, Algimantas;Tamoliūnaitė, Dovilė;Sabūnas, Vytautas;Karvelienė, Birutė
Title: Canine babesiosis in Lithuania
Is part of: Workshop on Arthropod-borne diseases transmitted by ticks, mites, fleas, and lice, 15-16 November 2018, Greifswald-Isle of Riems, Germany. Greifswald : Friedrich-Loeffler-Institut, 2018
Extent: p. 18-18
Date: 2018
Keywords: Babesia canis;Infectious disease;Canine babesiosis
Abstract: Canine babesiosis caused by Babesia canis is an emerging infectious disease in Europe. Although previously uncommon, canine babesiosishasbecome quite frequent in Lithuania during thepast decade. In the last few years an increasing number of cases with a wide variety of clinical signs have been recorded throughout the country. Expansion of B. canis in Baltic countries is associated mainly with the expanding range of the main vector - D. reticulatus and international travel. Genetic variability and antigenic variation are important mechanisms for the survival of Babesia parasites in their vertebrate hosts. Difference in the virulence of B. canis are associated with observed genetic heterogeneity among B. canis straisn. We have investigated the genetic diversity and distribution of B. canis strains isolated from naturally infected dogs in Lithuania. Blood samples from dogs suspected of babesiosis were collected across Lithuania during 2014-2017. PCR-RFLP assay and sequence analysis based on 185 rRNR gene and Bc28.1 gene (which encodes a GPlanchored merozoite surface antigen) were used for molecular characterization of B. canis strains. The molecular analysis indicates the presence of genetically heterogenic strains of B. canis in Lithuania: five genotypes of B. canis were identified based on 185 rRNR gene, while ten different Bc28.1 gene sequence variants which divided into three genetically distinct groups were identified. The distribution of B. canis genotypes in Lithuania was not homogenic and showed similarity to North-East and South-West Europe findings
Internet: https://hdl.handle.net/20.500.12259/60087
Affiliation(s): Biologijos katedra
Gamtos mokslų fakultetas
Lietuvos sveikatos mokslų universitetas. Veterinarijos akademija
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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