Please use this identifier to cite or link to this item:https://hdl.handle.net/20.500.12259/58351
Type of publication: Konferencijų tezės nerecenzuojamuose leidiniuose / Conference theses in non-peer-reviewed publications (T2)
Field of Science: Biochemija / Biochemistry (N004)
Author(s): Šepetytė, Kamilė;Sakalauskaitė, Sandra;Daugelavičius, Rimantas
Title: Analysis of efflux activity in Listeria monocytogenes cells
Is part of: COINS 2018: 13th international conference of life sciences, 28 February – 2 March 2018: book of abstracts. Vilnius: Vilniaus universitetas, Gyvybės mokslų centras, 2018
Extent: p. 103-104
Date: 2018
Keywords: Listeria monocytogenes;Food poisoning;Efflux inhibiting effect
Abstract: Introduction: Listeria monocytogenes is an opportunistic foodborne Gram-positive pathogen causing serious human infections. These bacteria are widely distributed in the environment and are the third most common cause of death from food poisoning. Because of efflux pumps L. monocytogenes is a multidrug resistant pathogen, not sensitive to many antimicrobial compounds, including tetracycline, amoxicillin, benzalkonium chloride. Efflux pumps are membrane transporters which can extrude out of the cells various toxic compounds. Knowledge about the regulation of activity of these pumps could enhance the efficiency of treatment. One of ideas how to control the efflux is to use the pump inhibitors. Aim: To assessthe influence of potential inhibitors on the interaction of L. monocytogenes cells with efflux indicator Tetraphenylphosphonium (TPP+) ions.[...]
Internet: http://thecoins.eu/wp-content/uploads/2018/03/Coins-2018-Abstract-book.pdf
Affiliation(s): Biochemijos katedra
Gamtos mokslų fakultetas
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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