Acrylic continuous beds for bioseparation: synthesis and characterization
Date | Start Page | End Page |
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2017 | 68 | 68 |
URI | Access Rights |
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https://hdl.handle.net/20.500.12259/57405 | |
Leidinys konferencijos svetainėje | Viso teksto dokumentas (atviroji prieiga) / Full Text Document (Open Access) |
Continuous beds, also described as monoliths, are the fourth generation of stationary phases. S. Hjertén was the first who published about continuous beds fabrication and application of high-performance liquid chromatography in 1989 [1]. Since then continuous beds have gained a lot of interest, because of its easy preparation and rapid high-efficiency separation. Over the years, there is a trend of miniaturization and for this reason, capillary monolith columns are a great solution. In this work a reviewed how capillary for liquid chromatography is modified using Bind Silane, how during in situ polymerization continuous bed columns are prepared using a solution of acrylic monomers and other additional compounds will be described [2]. Additionally, an evaluation of porosity, hydrodynamic properties and other characteristics of continuous beds will be reviewed [3].