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Type of publication: Straipsnis Clarivate Analytics Web of Science ar/ir Scopus / Article in Clarivate Analytics Web of Science or / and Scopus (S1)
Field of Science: Ekologija ir aplinkotyra / Ecology and environmental sciences (N012)
Author(s): Pedersen, Marie;Gehring, Ulrike;Beelen, Rob;Wang, Meng;Giorgis-Allemand, Lise;Nybo Andersen, Anne-Marie;Basagaña, Xavier;Bernard, Claire;Cirach, Marta;Forastiere, Francesco;Hoogh, Kees de;Gražulevičienė, Regina;Gruzieva, Olena;Hoek, Gerard;Jedynska, Aleksandra;Klümper, Claudia;Kooter, Ingeborg M;Krämer, Ursula;Kukkonen, Jaakko;Porta, Daniela;Postma, Dirkje S;Raaschou-Nielsen, Ole;Rossem, Lenie van;Sunyer, Jordi;Sørensen, Mette;Tsai, Ming-Yi;Vrijkotte, Tanja G. M;Wilhelm, Michael;Nieuwenhuijsen, Mark J;Pershagen, Göran;Brunekreef, Bert;Kogevinas, Manolis;Slama, Rémy
Title: Elemental constituents of particulate matter and newborn’s size in eight European cohorts
Is part of: Environmental health perspectives. Research Triangle Park, USA : National Institute of Environmental Health Sciences, 2016, Vol. 124, iss. 1
Extent: p. 141-150
Date: 2016
Keywords: Newborn's size;Particulate matter
Abstract: Background: The health effects of suspended particulate matter (PM) may depend on its chemical composition. Associations between maternal exposure to chemical constituents of PM and newborn’s size have been little examined. Aim: We aimed to investigate the associations of exposure to elemental constituents of PM with term low birth weight (LBW, weight<2,500 g among births after 37 weeks of gestation), mean birth weight and head circumference, relying on standardised fine-scale exposure assessment and with extensive control for potential confounders. Methods: We pooled data from eight European cohorts comprising 34,923 singleton births in 1994–2008. Annual average concentrations of elemental constituents of PM smaller than 2.5 and 10 μm (PM2.5 and PM10) at maternal home addresses during pregnancy were estimated using land-use regression models. Adjusted associations between each birth measurement and concentrations of eight elements (copper, iron, potassium, nickel, sulfur, silicon, vanadium and zinc) were calculated using random-effects regression on pooled data. Results: A 200 ng/m3 increase in sulfur in PM2.5 was associated with an increased risk of LBW (adjusted odds ratio, 1.36, 95% confidence interval: 1.17, 1.58). Increased nickel and zinc in PM2.5 concentrations were also associated with an increased risk of LBW. Head circumference was reduced at higher exposure to all elements except potassium. All associations with sulfur were most robust to adjustment for PM2.5 mass concentration. All results were similar for PM10. Conclusion: Sulfur, reflecting secondary combustion particles in this study, may adversely affect LBW and head circumference, independently of particle mass
Affiliation(s): Aplinkotyros katedra
Gamtos mokslų fakultetas
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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