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Type of publication: Konferencijų tezės nerecenzuojamuose leidiniuose / Conference theses in non-peer-reviewed publications (T2)
Field of Science: Biochemija / Biochemistry (N004)
Author(s): Kaselis, Andrius;Treinys, Rimantas;Vosyliūtė, Rūta;Šatkauskas, Saulius
Title: Sema3A and NGF in regeneration of sensory axons
Is part of: Fifth conference of Lithuanian Neuroscience Association : program and abstracts : 6-7 December, 2013, Vilnius, Lithuania / Lithuanian Neuroscience Association. Vilnius : Lithuanian Neuroscience Association, 2013
Extent: p. 28-28
Date: 2013
Keywords: Aksonų augimas;Aksonų vystymąsis;Semaforinas 3A;Nervų regeneracija;Nervų augimo faktorius;Axons;Physiology;Semaphorin-3A;Nerve growth factors;Physiology
Abstract: Regeneration of nervous system is complex and complicated process that involves neuron survival after injury as well as elongation of neurites and their guidance to final targets. Dorsal root ganglion (DRG) sensory neuron axon growth is highly impeded when they encounter neuronal growth cone-collapsing factor semaphorin3A (Sema3A) in both regeneration of adult nervous system and development of nervous system in embryonic stages. On the other hand, precise guidance of axon is mediated by many factors and increasing evidence shows that DRG axon development in both pathological and physiological conditions can be stimulated by nerve growth factor (NGF). The aim of this study was to evaluate the potential of increased NGF concentration to abolish Sema3A induced inhibitory responses in regenerating fifteen days old mouse embryo (e15) DRG axons in vitro. [...]
Affiliation(s): Biologijos katedra
Gamtos mokslų fakultetas
Lietuvos sveikatos mokslų universitetas. Kardiologijos institutas
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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