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dc.contributor.authorPedersen, Marie-
dc.contributor.authorGiorgis-Allemand, Lise-
dc.contributor.authorBernard, Claire-
dc.contributor.authorAguilera, Inmaculada-
dc.contributor.authorNybo Andersen, Anne Marie-
dc.contributor.authorBallester, Ferran-
dc.contributor.authorBeelen, Rob M. J-
dc.contributor.authorChatzi, Leda-
dc.contributor.authorCirach, Marta-
dc.contributor.authorDanilevičiutė, Asta-
dc.contributor.authorDėdelė, Audrius-
dc.contributor.authorEijsden, Manon van-
dc.contributor.authorEstarlich, Marisa-
dc.contributor.authorFernández-Somoano, Ana-
dc.contributor.authorFernández, Mariana F-
dc.contributor.authorForastiere, Francesco-
dc.contributor.authorGehring, Ulrike-
dc.contributor.authorGražulevičienė, Regina-
dc.description.abstractMethods. We pooled data from 14 population-based mother–child cohort studies in 12 European countries. Overall, the study population included 74 178 women who had singleton deliveries between Feb 11, 1994, and June 2, 2011, and for whom information about infant birthweight, gestational age, and sex was available. The primary outcome of interest was low birthweight at term (weight <2500 g at birth after 37 weeks of gestation). Mean concentrations of particulate matter with an aerodynamic diameter of less than 2•5 μm (PM2•5), less than 10 μm (PM10), and between 2•5 μm and 10 μm during pregnancy were estimated at maternal home addresses with temporally adjusted land-use regression models, as was PM2•5 absorbance and concentrations of nitrogen dioxide (NO2) and nitrogen oxides. We also investigated traffic density on the nearest road and total traffic load. We calculated pooled effect estimates with random-effects models. Findings. A 5 μg/m3 increase in concentration of PM2•5 during pregnancy was associated with an increased risk of low birthweight at term (adjusted odds ratio [OR] 1•18, 95% CI 1•06–1•33). An increased risk was also recorded for pregnancy concentrations lower than the present European Union annual PM2•5 limit of 25 μg/m3 (OR for 5 μg/m3 increase in participants exposed to concentrations of less than 20 μg/m3 1•41, 95% CI 1•20–1•65). PM10 (OR for 10 μg/m3 increase 1•16, 95% CI 1•00–1•35), NO2 (OR for 10 μg/m3 increase 1•09, 1•00–1•19), and traffic density on nearest street (OR for increase of 5000 vehicles per day 1•06, 1•01–1•11) were also associated with increased risk of low birthweight at term. The population attributable risk estimated for a reduction in PM2•5 concentration to 10 μg/m3 during pregnancy corresponded to a decrease of 22% (95% CI 8–33%) in cases of low birthweight at term. [...]en
dc.description.sponsorshipAplinkotyros katedra-
dc.description.sponsorshipGamtos mokslų fakultetas-
dc.description.sponsorshipVytauto Didžiojo universitetas-
dc.format.extentp. 695-704-
dc.relation.ispartofLancet respiratory medicine [elektroninis išteklius]. Amsterdam : Elsevier B.V., 2013, vol. 1, iss. 9-
dc.subjectAir pollutionen
dc.subjectLow birthweighten
dc.subjectESCAPE projecten
dc.subject.otherEkologija ir aplinkotyra / Ecology and environmental sciences (N012)-
dc.titleAmbient air pollution and low birthweight : a European cohort study (ESCAPE)en
dc.typeStraipsnis kitose duomenų bazėse / Article in other databases (S4)-
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