Analysis of phytochemical composition and antibacterial activity in medicinal plant Myrrhis odorata L

Abstract

The antibacterial activity of Myrrhis odorata L. was tested by the method of series dilutions, against different bacteria species. Investigated microorganisms were Escherichia coli, Proteus vulgaris and Staphylococcus aureus with and without antibiotic resistances mostly originating from healthy livestock. The extract from Myrrhis odorata L. showed antimicrobial activity against the investigated bacteria.A minimal inhibitory concentration (MIC) was applied as a method of measurement of the phytochemical activity. Preliminary results show that the MIC range between 8 – 13%.The most sensitive bacteria wasProteus vulgaris, an isolate without antibiotic resistance used for the official testing of disinfections withMIC of 8 %. The variations in the content and chemical composition of Myrrhis odorata L. have been grown in Lithuania were determined by gas chromatography/mass spectrometry (GC/MS). The highest content and diversity of compounds was determined during the full-flowering stage. The main components were anetole, methyleugenol, germacrene.